Groundbreaking vocals. The Techtonics were founded to help sociopathic male science and engineering students at Imperial College escape the library and discover life after labs. They present a rocking line-up of chart hits in original a cappella arrangements. www.thetechtonics.co.uk

EM Lewis’ new award-winning play follows Phan, a Cambodian refugee turned science teacher. He is forced to use his knowledge of extinction and survival to save a student and help the boy’s dying mother. Find us on myspace.com.

Defeat the Cyberwitch with real sonic screwdrivers! Disable Exterminators with the Doctor! Professional interactive theatre: kids come onstage throughout! ‘Take, make, bend time to see this show!’ ***** (BroadwayBaby.com). ***** (BritishTheatreGuide.info). www.spotlites.co.uk

Sequel to Fringe Report Award-winning ‘The Science Of Sex’; Funny Women finalist delves further into the science of attraction and love. ‘Wonderful’ (Time Out); ‘Had her audience in stitches’ (Diva); ‘Hilarious’ (Insidecomedy.co.uk).

Robin Ince plus guests celebrate everything. Be inspired about the universe and all that lies within it. May not contain everything about universe due to time constraints. All new for 2010.

A psychiatric clinic for girls attempts to replace superstition with science. Steven Levenson’s world premiere dark comedy about the perils of self-discovery at the intersection of modernity and madness. From two-time Fringe First-winning Red Chair Players.

Could you be infected? In a post-swine flu era, acclaimed medic troupe tictek return to save you from the latest, trendiest mind-eating disease. ‘Witty, challenging, debate-provoking’ (ThreeWeeks). Shortlisted for the IdeasFund Edinburgh Award.

Doubling in size for its 175th anniversary with even more interactive fun. Will you find your way out of the magical mirror maze? Can you shrink yourself like Alice in Wonderland in the amazing Ames room?

Peter Campbell-Wells returns to the Edinburgh Festival Fringe to blow big raspberries at the serious po-faced world of psychic entertainment. Mind reading and clairvoyance is absurd and Pete’s show revels in the daftness of it all! Free Show. www.petesmental.co.uk

Delve into a wonderland where lab coats intertwine and cells burst with light and discover the story of the forgotten genius Rosalind Franklin. Compelling original music and a talented ensemble unravel the mysterious beauty of the double helix.